Changes between Version 17 and Version 18 of public


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Timestamp:
May 5, 2009, 2:47:44 PM (15 years ago)
Author:
rolfe
Comment:

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  • public

    v17 v18  
    2222Specifically, we investigate how this bacterium senses oxygen, or the associated changes in oxidation/reduction balance, via the Fnr and ArcA proteins, how these systems interact with other regulatory systems, and how the redox response of an ''E. coli'' population is generated from the responses of single cells. There are five sub-projects to determine system properties and behaviour and three sub-projects to employ different and complementary modelling approaches using published data sets and data emerging from our own work. We construct increasingly elaborate models of the system at different levels of detail, which are used to generate new hypotheses and influence further experimental design.
    2323==== Workpackages ====
    24 || WP1.1 Molecular Interations & Regulatory Modules (Poole & Green) || WP1.2 Carbon & Electron Fluxes (Teixeira de Mattos) || WP13 WP1.3 Isogenic Mutants (Bettenbrock) || WP14 WP1.4 Single Cells (Bettenbrock & Gilles)||
     24|| [wiki:public/WP1.1   WP1.1 Molecular Interations & Regulatory Modules (Poole & Green)] || WP1.2 Carbon & Electron Fluxes (Teixeira de Mattos) || WP13 WP1.3 Isogenic Mutants (Bettenbrock) || WP14 WP1.4 Single Cells (Bettenbrock & Gilles)||
    2525|| [wiki:public/WP2.1.1   WP2.1.1 Agent-based Modelling (Holcombe & Maleki-Dizaji)] || [wiki:public/WP2.1.2 WP2.1.2 From ''Escherichia coli'' Workflow using Taverna and Web Services (Holcombe & Maleki-Dizaji & Rolfe)] ||WP2.2 Reduced-order modelling (Gilles) ||  [wiki:public/WP23 WP2.3 Detailed Kinetic Modelling (Sauter & Sawodny)] ||
    2626==== Personal Pages ====